Genferon 1000000ME  No. 10

Genferon 1000000ME No. 10

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Genferon 1000000ME No.10

Composition:
recombinant human interferon alpha-2 1 million IU taurine 10 mg benzocaine 55 mg Excipients: solid fat, dextran 60,000, polyethylene oxide 1500, tween-80, emulsifier T2, sodium citrate, citric acid, purified water.

Pharmacokinetics:
With rectal administration of the drug, a high bioavailability (over 80%) of interferon is noted, in connection with which both local and pronounced systemic immunomodulatory effects are achieved; with intravaginal use due to the high concentration in the focus of infection and fixation on the cells of the mucous membrane, a pronounced local antiviral, antiproliferative and antibacterial effect is achieved, while the systemic effect due to the low absorption capacity of the vaginal mucosa is insignificant. Cmax of interferon in blood serum is reached 5 hours after drug administration. The main route of elimination is renal catabolism. T1 / 2 is 12 hours, which makes it necessary to use the drug 2 times a day.

Special conditions:
To prevent urogenital reinfection, it is recommended to consider the simultaneous treatment of a sexual partner. The use of the drug during menstruation is allowed. Genferon® does not affect the performance of potentially hazardous activities that require special attention and quick reactions (driving vehicles, machinery, etc.).

Indications:
As part of complex therapy for infectious and inflammatory diseases of the urogenital tract:
- genital herpes;
- chlamydia;
- ureaplasmosis;
- mycoplasmosis;
- recurrent vaginal candidiasis;
- gardnerellosis;
- trichomoniasis;
- papillomavirus infections;
- bacterial vaginosis;
- cervical erosion;
- cervicitis;
- vulvovaginitis;
- bartholinitis;
- adnexitis;
- prostatitis;
- urethritis;
- balanitis;
- balanoposthitis.